Apv Focus Group Drug Delivery
نویسندگان
چکیده
For the second time in the last three years the Skin Forum held its Annual Meeting in conjunction with the APV. This time the meeting took place in Prague at the IMG Conference Centre with the APV Headquarters in the form of Dr. Bornhöft and Ms. Schmidt leading the meeting organizational efforts. About 200 skin scientists attended the meeting and gave it, with their discussions in the lectures and at the posters, a lively and stimulating atmosphere. The location of historic and beautiful Prague only added to the enjoyment of the meeting.
منابع مشابه
Effects of Emulsion Composition on Pulmonary Tobramycin Delivery During Antibacterial Perfluorocarbon Ventilation.
BACKGROUND The effectiveness of inhaled aerosolized antibiotics is limited by poor ventilation of infected airways. Pulmonary delivery of antibiotics emulsified within liquid perfluorocarbon [antibacterial perfluorocarbon ventilation (APV)] may solve this problem through better airway penetration and improved spatial uniformity. However, little work has been done to explore emulsion formulation...
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BACKGROUND Aerosolized delivery of antibiotics is hindered by poor penetration within distal and plugged airways. Antibacterial perfluorocarbon ventilation (APV) is a proposed solution in which the lungs are partially or totally filled with perfluorocarbon (PFC) containing emulsified antibiotics. The purpose of this study was to evaluate emulsion stability and rheological, antibacterial, and ph...
متن کاملراهبردهای افزایش نفوذ در دارورسانی پوستی
Transdermal drug delivery (TDD) is a non-invasive, topical administration method for therapeutic agents. Transdermal delivery also has advantages including providing release for long periods of time, improving patient compliance, and generally being inexpensive. Despite these advantages, the use of TDD has been limited by innate barrier functions of the skin. Only small (<500 Da), lipophilic mo...
متن کاملGenotypic and phenotypic evolution of HIV type-1 protease during in vitro sequential or concomitant combination of atazanavir and amprenavir.
BACKGROUND The pathways of resistance to atazanavir (ATV) and amprenavir (APV) converge at position 50 of HIV protease. The determinants of cross-resistance were analysed during in vitro sequential or concomitant combination pressure with both drugs. METHODS Recombinant viruses containing in vitro and in vivo selected I50L and I50V proteases were constructed and cultured in increasing concent...
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BACKGROUND Amprenavir (APV), fosamprenavir (FPV), lopinavir (LPV), ritonavir (RTV) and efavirenz (EFV) are to varying degrees substrates, inducers and inhibitors of CYP3A4. Coadministration of these drugs might result in complex pharmacokinetic drug-drug interactions. METHODS Two prospective, open-label, non-randomized studies evaluated APV and LPV steady-state pharmacokinetics in HIV-infecte...
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